MST4 kinase suppresses gastric tumorigenesis by limiting YAP activation via a non-canonical pathway

Hyperactivation of YAP has been commonly associated with tumorigenesis, and emerging evidence hints at multilayered Hippo-independent regulations of YAP. In this study, we identified a new MST4–YAP axis, which acts as a noncanonical Hippo signaling pathway that limits stress-induced YAP activation....

Descripción completa

Detalles Bibliográficos
Autores principales: An, Liwei, Nie, Pingping, Chen, Min, Tang, Yang, Zhang, Hui, Guan, Jingmin, Cao, Zhifa, Hou, Chun, Wang, Wenjia, Zhao, Yun, Xu, Huixiong, Jiao, Shi, Zhou, Zhaocai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971137/
https://www.ncbi.nlm.nih.gov/pubmed/32271880
http://dx.doi.org/10.1084/jem.20191817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971137/
https://www.ncbi.nlm.nih.gov/pubmed/32271880
http://dx.doi.org/10.1084/jem.20191817

Ejemplares similares