Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer

Gene dosage is a key defining factor to understand cancer pathogenesis and progression, which requires the development of experimental models that aid better deconstruction of the disease. Here, we model an aggressive form of prostate cancer and show the unconventional association of LKB1 dosage to...

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Detalles Bibliográficos
Autores principales: Hermanova, Ivana, Zúñiga-García, Patricia, Caro-Maldonado, Alfredo, Fernandez-Ruiz, Sonia, Salvador, Fernando, Martín-Martín, Natalia, Zabala-Letona, Amaia, Nuñez-Olle, Marc, Torrano, Verónica, Camacho, Laura, Lizcano, Jose M., Talamillo, Ana, Carreira, Suzanne, Gurel, Bora, Cortazar, Ana R., Guiu, Marc, López, Jose I., Martinez-Romero, Anabel, Astobiza, Ianire, Valcarcel-Jimenez, Lorea, Lorente, Mar, Arruabarrena-Aristorena, Amaia, Velasco, Guillermo, Gomez-Muñoz, Antonio, Suárez-Cabrera, Cristian, Lodewijk, Iris, Flores, Juana M., Sutherland, James D., Barrio, Rosa, de Bono, Johann S., Paramio, Jesús M., Trka, Jan, Graupera, Mariona, Gomis, Roger R., Carracedo, Arkaitz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971141/
https://www.ncbi.nlm.nih.gov/pubmed/32219437
http://dx.doi.org/10.1084/jem.20191787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971141/
https://www.ncbi.nlm.nih.gov/pubmed/32219437
http://dx.doi.org/10.1084/jem.20191787

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