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Inosine induces acute hyperuricaemia in rhesus monkey (Macaca mulatta) as a potential disease animal model
CONTEXT: The uric acid metabolism pathway is more similar in primates and humans than in rodents. However, there are no reports of using primates to establish animal models of hyperuricaemia (HUA). OBJECTIVES: To establish an animal model highly related to HUA in humans. MATERIALS AND METHODS: Inosi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971274/ https://www.ncbi.nlm.nih.gov/pubmed/33715593 http://dx.doi.org/10.1080/13880209.2020.1871373 |