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Inosine induces acute hyperuricaemia in rhesus monkey (Macaca mulatta) as a potential disease animal model

CONTEXT: The uric acid metabolism pathway is more similar in primates and humans than in rodents. However, there are no reports of using primates to establish animal models of hyperuricaemia (HUA). OBJECTIVES: To establish an animal model highly related to HUA in humans. MATERIALS AND METHODS: Inosi...

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Detalles Bibliográficos
Autores principales: Tang, Dong-hong, Wang, Chen-yun, Huang, Xi, Yi, Hong-kun, Li, Zhe-li, Ma, Kai-li, Ye, You-song, Zhang, Jian-wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971274/
https://www.ncbi.nlm.nih.gov/pubmed/33715593
http://dx.doi.org/10.1080/13880209.2020.1871373

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