Re-polarization of immunosuppressive macrophages to tumor-cytotoxic macrophages by repurposed metabolic drugs

M2-like tumor-associated macrophages promote tumor progression by establishing an immunosuppressive tumor microenvironment. The phenotype and activity of immunosuppressive macrophages are related to their mitochondrial metabolism. Thus, we studied if drugs targeting mitochondrial metabolic pathways...

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Detalles Bibliográficos
Autores principales: Oyarce, Cesar, Vizcaino-Castro, Ana, Chen, Shipeng, Boerma, Annemarie, Daemen, Toos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971325/
https://www.ncbi.nlm.nih.gov/pubmed/33796407
http://dx.doi.org/10.1080/2162402X.2021.1898753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971325/
https://www.ncbi.nlm.nih.gov/pubmed/33796407
http://dx.doi.org/10.1080/2162402X.2021.1898753

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