Extended Duration Infusion of Hydroxocobalamin for Vasoplegic Rescue in Septic Shock

Nitric oxide (NO) is a gaseous signaling molecule and a key endogenous mediator of vascular tone. Hydroxocobalamin (HCB) affects NO-mediated vasoplegia as (1) a direct inhibitor of nitric oxide synthase (NOS), thereby decreasing its production, and (2) by binding directly to NO and acting as a scave...

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Detalles Bibliográficos
Autores principales: Gerdes, Harrison J, Seelhammer, Troy G, Nei, Scott, Diaz Soto, Juan, Nabzdyk, Christoph G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Anesthesiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971717/
https://www.ncbi.nlm.nih.gov/pubmed/33754111
http://dx.doi.org/10.7759/cureus.13388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971717/
https://www.ncbi.nlm.nih.gov/pubmed/33754111
http://dx.doi.org/10.7759/cureus.13388

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