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Extended Duration Infusion of Hydroxocobalamin for Vasoplegic Rescue in Septic Shock

Nitric oxide (NO) is a gaseous signaling molecule and a key endogenous mediator of vascular tone. Hydroxocobalamin (HCB) affects NO-mediated vasoplegia as (1) a direct inhibitor of nitric oxide synthase (NOS), thereby decreasing its production, and (2) by binding directly to NO and acting as a scave...

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Detalles Bibliográficos
Autores principales:	Gerdes, Harrison J, Seelhammer, Troy G, Nei, Scott, Diaz Soto, Juan, Nabzdyk, Christoph G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cureus 2021
Materias:	Anesthesiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971717/ https://www.ncbi.nlm.nih.gov/pubmed/33754111 http://dx.doi.org/10.7759/cureus.13388

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