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A computational study of co-inhibitory immune complex assembly at the interface between T cells and antigen presenting cells

The activation and differentiation of T-cells are mainly directly by their co-regulatory receptors. T lymphocyte-associated protein-4 (CTLA-4) and programed cell death-1 (PD-1) are two of the most important co-regulatory receptors. Binding of PD-1 and CTLA-4 with their corresponding ligands programe...

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Detalles Bibliográficos
Autores principales: Su, Zhaoqian, Dhusia, Kalyani, Wu, Yinghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971848/
https://www.ncbi.nlm.nih.gov/pubmed/33684103
http://dx.doi.org/10.1371/journal.pcbi.1008825