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A computational study of co-inhibitory immune complex assembly at the interface between T cells and antigen presenting cells
The activation and differentiation of T-cells are mainly directly by their co-regulatory receptors. T lymphocyte-associated protein-4 (CTLA-4) and programed cell death-1 (PD-1) are two of the most important co-regulatory receptors. Binding of PD-1 and CTLA-4 with their corresponding ligands programe...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971848/ https://www.ncbi.nlm.nih.gov/pubmed/33684103 http://dx.doi.org/10.1371/journal.pcbi.1008825 |