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Complementary phase responses via functional differentiation of dual negative feedback loops

Multiple feedback loops are often found in gene regulations for various cellular functions. In mammalian circadian clocks, oscillations of Period1 (Per1) and Period2 (Per2) expression are caused by interacting negative feedback loops (NFLs) whose protein products with similar molecular functions rep...

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Detalles Bibliográficos
Autores principales: Uriu, Koichiro, Tei, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971863/
https://www.ncbi.nlm.nih.gov/pubmed/33684114
http://dx.doi.org/10.1371/journal.pcbi.1008774