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The evolutionary origin of the universal distribution of mutation fitness effect

An intriguing fact long defying explanation is the observation of a universal exponential distribution of beneficial mutations in fitness effect for different microorganisms. To explain this effect, we use a population model including mutation, directional selection, linkage, and genetic drift. The...

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Detalles Bibliográficos
Autores principales:	Barlukova, Ayuna, Rouzine, Igor M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971868/ https://www.ncbi.nlm.nih.gov/pubmed/33684109 http://dx.doi.org/10.1371/journal.pcbi.1008822

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