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A multiscale model via single-cell transcriptomics reveals robust patterning mechanisms during early mammalian embryo development
During early mammalian embryo development, a small number of cells make robust fate decisions at particular spatial locations in a tight time window to form inner cell mass (ICM), and later epiblast (Epi) and primitive endoderm (PE). While recent single-cell transcriptomics data allows scrutinizatio...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971879/ https://www.ncbi.nlm.nih.gov/pubmed/33684098 http://dx.doi.org/10.1371/journal.pcbi.1008571 |