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Low-dose hydralazine during gestation reduces renal fibrosis in rodent offspring exposed to maternal high fat diet

BACKGROUND: Maternal high fat diet (HFD) promotes chronic kidney disease (CKD) in offspring. This is in accordance with the theory of fetal programming, which suggests adverse conditions occurring in utero predispose offspring to chronic conditions later in life. DNA methylation has been proposed as...

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Detalles Bibliográficos
Autores principales: Larkin, Benjamin P., Saad, Sonia, Glastras, Sarah J., Nguyen, Long T., Hou, Miao, Chen, Hui, Wang, Rosy, Pollock, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971884/
https://www.ncbi.nlm.nih.gov/pubmed/33735324
http://dx.doi.org/10.1371/journal.pone.0248854