JMJD6 negatively regulates cytosolic RNA induced antiviral signaling by recruiting RNF5 to promote activated IRF3 K48 ubiquitination

The negative regulation of antiviral immune responses is essential for the host to maintain homeostasis. Jumonji domain-containing protein 6 (JMJD6) was previously identified with a number of functions during RNA virus infection. Upon viral RNA recognition, retinoic acid-inducible gene-I-like recept...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Wang, Qi, Yang, Fan, Zhu, Zixiang, Duan, Yueyue, Yang, Yang, Cao, Weijun, Zhang, Keshan, Ma, Junwu, Liu, Xiangtao, Zheng, Haixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971890/
https://www.ncbi.nlm.nih.gov/pubmed/33684176
http://dx.doi.org/10.1371/journal.ppat.1009366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971890/
https://www.ncbi.nlm.nih.gov/pubmed/33684176
http://dx.doi.org/10.1371/journal.ppat.1009366

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