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JMJD6 negatively regulates cytosolic RNA induced antiviral signaling by recruiting RNF5 to promote activated IRF3 K48 ubiquitination
The negative regulation of antiviral immune responses is essential for the host to maintain homeostasis. Jumonji domain-containing protein 6 (JMJD6) was previously identified with a number of functions during RNA virus infection. Upon viral RNA recognition, retinoic acid-inducible gene-I-like recept...
Autores principales: | Zhang, Wei, Wang, Qi, Yang, Fan, Zhu, Zixiang, Duan, Yueyue, Yang, Yang, Cao, Weijun, Zhang, Keshan, Ma, Junwu, Liu, Xiangtao, Zheng, Haixue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971890/ https://www.ncbi.nlm.nih.gov/pubmed/33684176 http://dx.doi.org/10.1371/journal.ppat.1009366 |
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