MOSTWAS: Multi-Omic Strategies for Transcriptome-Wide Association Studies

Traditional predictive models for transcriptome-wide association studies (TWAS) consider only single nucleotide polymorphisms (SNPs) local to genes of interest and perform parameter shrinkage with a regularization process. These approaches ignore the effect of distal-SNPs or other molecular effects...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Arjun, Li, Yun, Love, Michael I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971899/
https://www.ncbi.nlm.nih.gov/pubmed/33684137
http://dx.doi.org/10.1371/journal.pgen.1009398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971899/
https://www.ncbi.nlm.nih.gov/pubmed/33684137
http://dx.doi.org/10.1371/journal.pgen.1009398

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