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MOSTWAS: Multi-Omic Strategies for Transcriptome-Wide Association Studies
Traditional predictive models for transcriptome-wide association studies (TWAS) consider only single nucleotide polymorphisms (SNPs) local to genes of interest and perform parameter shrinkage with a regularization process. These approaches ignore the effect of distal-SNPs or other molecular effects...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971899/ https://www.ncbi.nlm.nih.gov/pubmed/33684137 http://dx.doi.org/10.1371/journal.pgen.1009398 |