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A network-informed analysis of SARS-CoV-2 and hemophagocytic lymphohistiocytosis genes’ interactions points to Neutrophil extracellular traps as mediators of thrombosis in COVID-19

Abnormal coagulation and an increased risk of thrombosis are features of severe COVID-19, with parallels proposed with hemophagocytic lymphohistiocytosis (HLH), a life-threating condition associated with hyperinflammation. The presence of HLH was described in severely ill patients during the H1N1 in...

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Detalles Bibliográficos
Autores principales: Ding, Jun, Hostallero, David Earl, El Khili, Mohamed Reda, Fonseca, Gregory Joseph, Milette, Simon, Noorah, Nuzha, Guay-Belzile, Myriam, Spicer, Jonathan, Daneshtalab, Noriko, Sirois, Martin, Tremblay, Karine, Emad, Amin, Rousseau, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971900/
https://www.ncbi.nlm.nih.gov/pubmed/33684134
http://dx.doi.org/10.1371/journal.pcbi.1008810