Investigating the relationships between unfavourable habitual sleep and metabolomic traits: evidence from multi-cohort multivariable regression and Mendelian randomization analyses

BACKGROUND: Sleep traits are associated with cardiometabolic disease risk, with evidence from Mendelian randomization (MR) suggesting that insomnia symptoms and shorter sleep duration increase coronary artery disease risk. We combined adjusted multivariable regression (AMV) and MR analyses of phenot...

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Detalles Bibliográficos
Autores principales: Bos, Maxime M., Goulding, Neil J., Lee, Matthew A., Hofman, Amy, Bot, Mariska, Pool, René, Vijfhuizen, Lisanne S., Zhang, Xiang, Li, Chihua, Mustafa, Rima, Neville, Matt J., Li-Gao, Ruifang, Trompet, Stella, Beekman, Marian, Biermasz, Nienke R., Boomsma, Dorret I., de Boer, Irene, Christodoulides, Constantinos, Dehghan, Abbas, van Dijk, Ko Willems, Ford, Ian, Ghanbari, Mohsen, Heijmans, Bastiaan T., Ikram, M. Arfan, Jukema, J. Wouter, Mook-Kanamori, Dennis O., Karpe, Fredrik, Luik, Annemarie I., Lumey, L. H., van den Maagdenberg, Arn M. J. M., Mooijaart, Simon P., de Mutsert, Renée, Penninx, Brenda W. J. H., Rensen, Patrick C. N., Richmond, Rebecca C., Rosendaal, Frits R., Sattar, Naveed, Schoevers, Robert A., Slagboom, P. Eline, Terwindt, Gisela M., Thesing, Carisha S., Wade, Kaitlin H., Wijsman, Carolien A., Willemsen, Gonneke, Zwinderman, Aeilko H., van Heemst, Diana, Noordam, Raymond, Lawlor, Deborah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971964/
https://www.ncbi.nlm.nih.gov/pubmed/33731105
http://dx.doi.org/10.1186/s12916-021-01939-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971964/
https://www.ncbi.nlm.nih.gov/pubmed/33731105
http://dx.doi.org/10.1186/s12916-021-01939-0

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