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KPNA2 interaction with CBX8 contributes to the development and progression of bladder cancer by mediating the PRDM1/c-FOS pathway

BACKGROUND: Bladder cancer (BCa) is a common malignancy characterized by high heterogeneity, yet the current treatment modalities are limited. The aim of the present investigation was to unravel the functional role of Karyopherin alpha 2 (KPNA2), a tumor facilitator identified in multiple malignanci...

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Detalles Bibliográficos
Autores principales: Zeng, Fanchang, Luo, Liumei, Li, Daoyuan, Guo, Juncheng, Guo, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7972191/
https://www.ncbi.nlm.nih.gov/pubmed/33731128
http://dx.doi.org/10.1186/s12967-021-02709-5