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Melatonin Ameliorates Hemorrhagic Transformation via Suppression of ROS-Induced NLRP3 Activation after Cerebral Ischemia in Hyperglycemic Rats

Melatonin is a strong antioxidant which beneficially protects against middle cerebral artery occlusion (MCAO) followed by hemorrhagic transformation in rats; protection includes the reduction of neurological deficits, infarction, and hematoma volume. The molecular mechanisms underlying these neuropr...

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Detalles Bibliográficos
Autores principales: Shao, Anwen, Gao, Shiqi, Wu, Haijian, Xu, Weilin, Pan, Yuanbo, Fang, Yuanjian, Wang, Xiaoyu, Zhang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7972845/
https://www.ncbi.nlm.nih.gov/pubmed/33777317
http://dx.doi.org/10.1155/2021/6659282