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Proinsulin:C-peptide ratio trajectories over time in relatives at increased risk of progression to type 1 diabetes
OBJECTIVE: Biomarkers are needed to characterize heterogeneity within populations at risk for type 1 diabetes. The ratio of proinsulin to C-peptide (PI:C ratio), has been proposed as a biomarker of beta cell dysfunction and is associated with progression to type 1 diabetes. However, relationships be...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7972972/ https://www.ncbi.nlm.nih.gov/pubmed/33748733 http://dx.doi.org/10.1016/j.jtauto.2021.100089 |