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Proinsulin:C-peptide ratio trajectories over time in relatives at increased risk of progression to type 1 diabetes

OBJECTIVE: Biomarkers are needed to characterize heterogeneity within populations at risk for type 1 diabetes. The ratio of proinsulin to C-peptide (PI:C ratio), has been proposed as a biomarker of beta cell dysfunction and is associated with progression to type 1 diabetes. However, relationships be...

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Detalles Bibliográficos
Autores principales: Triolo, Taylor M., Pyle, Laura, Seligova, Sona, Yu, Liping, Simmons, Kimber, Gottlieb, Peter, Evans-Molina, Carmella, Steck, Andrea K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7972972/
https://www.ncbi.nlm.nih.gov/pubmed/33748733
http://dx.doi.org/10.1016/j.jtauto.2021.100089