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Abrogating mitochondrial ROS in neurons or astrocytes reveals cell-specific impact on mouse behaviour

Cells naturally produce mitochondrial reactive oxygen species (mROS), but the in vivo pathophysiological significance has long remained controversial. Within the brain, astrocyte-derived mROS physiologically regulate behaviour and are produced at one order of magnitude faster than in neurons. Howeve...

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Detalles Bibliográficos
Autores principales: Vicente-Gutierrez, Carlos, Bonora, Nicolo, Jimenez-Blasco, Daniel, Lopez-Fabuel, Irene, Bates, Georgina, Murphy, Michael P., Almeida, Angeles, Bolaños, Juan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7972977/
https://www.ncbi.nlm.nih.gov/pubmed/33711713
http://dx.doi.org/10.1016/j.redox.2021.101917