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Recreating mouse cortico-hippocampal neuronal circuit in microfluidic devices to study BDNF axonal transport upon glucocorticoid treatment

BDNF levels are reduced in the chronically stressed brain, in the area of hippocampus. Part of the hippocampal BDNF is provided by neuronal projection of the entorhinal cortex. Studying the cortico-hippocampal transport of BDNF in vivo is technically difficult. Here, we describe a protocol that repr...

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Detalles Bibliográficos
Autores principales: Lenoir, Sophie, Genoux, Aurélie, Agasse, Fabienne, Saudou, Frédéric, Humbert, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7972978/
https://www.ncbi.nlm.nih.gov/pubmed/33748784
http://dx.doi.org/10.1016/j.xpro.2021.100382