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Generation of TCRα-transduced T cells for adoptive transfer therapy of salmonellosis in mice

Adoptive transfer therapy has great potential to treat diseases such as cancer as well as autoimmune and infectious diseases. Identification of chain-centric T cell receptors (TCRs) with the dominant-active antigen-specific α-chains (TCRα) can significantly improve the efficacy of adoptive cell ther...

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Detalles Bibliográficos
Autores principales: Kalinina, Anastasiia, Bruter, Alexandra, Nesterenko, Ludmila, Khromykh, Ludmila, Kazansky, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7972981/
https://www.ncbi.nlm.nih.gov/pubmed/33748782
http://dx.doi.org/10.1016/j.xpro.2021.100368