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Generation of TCRα-transduced T cells for adoptive transfer therapy of salmonellosis in mice
Adoptive transfer therapy has great potential to treat diseases such as cancer as well as autoimmune and infectious diseases. Identification of chain-centric T cell receptors (TCRs) with the dominant-active antigen-specific α-chains (TCRα) can significantly improve the efficacy of adoptive cell ther...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7972981/ https://www.ncbi.nlm.nih.gov/pubmed/33748782 http://dx.doi.org/10.1016/j.xpro.2021.100368 |