Multi-Modal Characterization of Monocytes in Idiopathic Pulmonary Fibrosis Reveals a Primed Type I Interferon Immune Phenotype

Idiopathic pulmonary fibrosis (IPF) is the most severe form of chronic lung fibrosis. Circulating monocytes have been implicated in immune pathology in IPF but their phenotype is unknown. In this work, we determined the immune phenotype of monocytes in IPF using multi-colour flow cytometry, RNA sequ...

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Detalles Bibliográficos
Autores principales: Fraser, Emily, Denney, Laura, Antanaviciute, Agne, Blirando, Karl, Vuppusetty, Chaitanya, Zheng, Yuejuan, Repapi, Emmanouela, Iotchkova, Valentina, Taylor, Stephen, Ashley, Neil, St Noble, Victoria, Benamore, Rachel, Hoyles, Rachel, Clelland, Colin, Rastrick, Joseph M. D., Hardman, Clare S., Alham, Nasullah K., Rigby, Rachel E., Simmons, Alison, Rehwinkel, Jan, Ho, Ling-Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973086/
https://www.ncbi.nlm.nih.gov/pubmed/33746960
http://dx.doi.org/10.3389/fimmu.2021.623430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973086/
https://www.ncbi.nlm.nih.gov/pubmed/33746960
http://dx.doi.org/10.3389/fimmu.2021.623430

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