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Antiretroviral Treatment-Induced Decrease in Immune Activation Contributes to Reduced Susceptibility to Tuberculosis in HIV-1/Mtb Co-infected Persons

Antiretroviral treatment (ART) reduces the risk of developing active tuberculosis (TB) in HIV-1 co-infected persons. In order to understand host immune responses during ART in the context of Mycobacterium tuberculosis (Mtb) sensitization, we performed RNAseq analysis of whole blood-derived RNA from...

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Detalles Bibliográficos
Autores principales: Wilkinson, Katalin A., Schneider-Luftman, Deborah, Lai, Rachel, Barrington, Christopher, Jhilmeet, Nishtha, Lowe, David M., Kelly, Gavin, Wilkinson, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973093/
https://www.ncbi.nlm.nih.gov/pubmed/33746987
http://dx.doi.org/10.3389/fimmu.2021.645446