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Ultrasound Combined With Microbubbles Loading BDNF Retrovirus to Open Blood–Brain Barrier for Treatment of Alzheimer’s Disease

Background: Brain-derived nerve growth factor (BDNF) is a promising effective target for the treatment of Alzheimer’s disease (AD). BDNF, which has a high molecular weight, has difficulty in crossing the blood–brain barrier (BBB). The study aimed to prepare microbubbles loading brain-derived nerve g...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Wei, Xi-Xi, Chang, Lian-Sheng, Dong, Lei, Wang, Yong-Ling, Li, Na-Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973107/
https://www.ncbi.nlm.nih.gov/pubmed/33746754
http://dx.doi.org/10.3389/fphar.2021.615104