Alginate hydrogel polymers enable efficient delivery of a vascular-targeted AAV vector into aortic tissue

Gene therapeutic approaches to aortic diseases require efficient vectors and delivery systems for transduction of endothelial cells (ECs) and smooth muscle cells (SMCs). Here, we developed a novel strategy to efficiently deliver a previously described vascular-specific adeno-associated viral (AAV) v...

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Detalles Bibliográficos
Autores principales: Remes, Anca, Basha, Dima Ibrahim, Puehler, Thomas, Borowski, Christopher, Hille, Susanne, Kummer, Laura, Wagner, Andreas H., Hecker, Markus, Soethoff, Jasmin, Lutter, Georg, Frank, Derk, Arif, Rawa, Frey, Norbert, Zaradzki, Marcin, Müller, Oliver J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973147/
https://www.ncbi.nlm.nih.gov/pubmed/33768132
http://dx.doi.org/10.1016/j.omtm.2021.02.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973147/
https://www.ncbi.nlm.nih.gov/pubmed/33768132
http://dx.doi.org/10.1016/j.omtm.2021.02.017

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