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Absence of Cytochrome P450-1b1 Increases Susceptibility of Pressure-Induced Axonopathy in the Murine Retinal Projection

Mutations in the cytochrome P450-1B1 (Cyp1b1) gene is a common genetic predisposition associated with various human glaucomas, most prominently in primary congenital glaucoma (PCG). The role of Cyp1b1 in the eye is largely unknown, however, its absence appears to drive the maldevelopment of anterior...

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Detalles Bibliográficos
Autores principales: Amirmokhtari, Naseem, Foresi, Brian D., Dewan, Shiv S., Bouhenni, Rachida A., Smith, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973214/
https://www.ncbi.nlm.nih.gov/pubmed/33748124
http://dx.doi.org/10.3389/fcell.2021.636321