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Fast Fluorine-18 labeling and preclinical evaluation of novel Mucin1 and its Folate hybrid peptide conjugate for targeting breast carcinoma

BACKGROUND: There is a need to develop new and more potent radiofluorinated peptide and their hybrid conjugates for multiple-receptors targeting properties that overexpress on many cancers. METHODS: We have synthesized MUC1-[(18)F] SFB and MUC1-FA-[(18)F] SFB hybrid conjugates using a convenient and...

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Detalles Bibliográficos
Autores principales: Al Jammaz, I., Al-Otaibi, B., Al-Malki, Y., Abousekhrah, A., Okarvi, S. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973340/
https://www.ncbi.nlm.nih.gov/pubmed/33738611
http://dx.doi.org/10.1186/s41181-021-00127-y