Cargando…

Fast Fluorine-18 labeling and preclinical evaluation of novel Mucin1 and its Folate hybrid peptide conjugate for targeting breast carcinoma

BACKGROUND: There is a need to develop new and more potent radiofluorinated peptide and their hybrid conjugates for multiple-receptors targeting properties that overexpress on many cancers. METHODS: We have synthesized MUC1-[(18)F] SFB and MUC1-FA-[(18)F] SFB hybrid conjugates using a convenient and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Al Jammaz, I., Al-Otaibi, B., Al-Malki, Y., Abousekhrah, A., Okarvi, S. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973340/ https://www.ncbi.nlm.nih.gov/pubmed/33738611 http://dx.doi.org/10.1186/s41181-021-00127-y

Ejemplares similares

Development of new copper-64 labeled rhodamine: a potential PET myocardial perfusion imaging agent
por: AlHokbany, Norah, et al.
Publicado: (2022)

A convenient and efficient total solid-phase synthesis of DOTA-functionalized tumor-targeting peptides for PET imaging of cancer
por: Okarvi, Subhani M., et al.
Publicado: (2019)

Development of the Tumor-Specific Antigen-Derived Synthetic Peptides as Potential Candidates for Targeting Breast and Other Possible Human Carcinomas
por: Okarvi, Subhani M., et al.
Publicado: (2019)

(18) F-click labeling and preclinical evaluation of a new (18) F-folate for PET imaging
por: Schieferstein, Hanno, et al.
Publicado: (2013)

Preclinical Evaluation of a Fluorine-18 Labeled Probe for the Detection of the Expression of PSMA Level in Cancer
por: Guo, Yirui, et al.
Publicado: (2021)

Preparation, Radiolabeling with (68)Ga/(177)Lu and Preclinical Evaluation of Novel Angiotensin Peptide Analog: A New Class of Peptides for Breast Cancer Targeting
por: Okarvi, Subhani M.
Publicado: (2023)

Fluorine-18 Labeled Fluorofuranylnorprogesterone ([(18)F]FFNP) and Dihydrotestosterone ([(18)F]FDHT) Prepared by “Fluorination on Sep-Pak” Method
por: Basuli, Falguni, et al.
Publicado: (2019)

Fluorine-18 Radiochemistry, Labeling Strategies and Synthetic Routes
por: Jacobson, Orit, et al.
Publicado: (2014)

The curcumin analog (PAC) suppressed cell survival and induced apoptosis and autophagy in oral cancer cells
por: Semlali, Abdelhabib, et al.
Publicado: (2021)

Fluorine-18 Labelled Radioligands for PET Imaging of Cyclooxygenase-2
por: Kaur, Jatinder, et al.
Publicado: (2022)

Synthesis and Evaluation of Fluorine-18-Labeled L-Rhamnose Derivatives
por: Zhang, Xiang, et al.
Publicado: (2023)

Automated Synthesis of Fluorine-18 Labeled CXCR4 Ligand via the Conjugation with Nicotinic Acid N-Hydroxysuccinimide Ester (6-[(18)F]SFPy)
por: Basuli, Falguni, et al.
Publicado: (2020)

Radioiodinated Naphthylalanine Derivatives Targeting Pancreatic Beta Cells in Normal and Nonobese Diabetic Mice
por: Amartey, John K., et al.
Publicado: (2008)

Preclinical evaluation of carbon-11 and fluorine-18 sulfonamide derivatives for in vivo radiolabeling of erythrocytes
por: Gheysens, Olivier, et al.
Publicado: (2013)

Fluorine-18 labeled amino acids for tumor PET/CT imaging
por: Qi, Yiqiang, et al.
Publicado: (2017)

Fluorine-18-Labeled Fluorescent Dyes for Dual-Mode Molecular Imaging
por: Munch, Maxime, et al.
Publicado: (2020)

Synthesis and pharmacokinetic characterisation of a fluorine-18 labelled brain shuttle peptide fusion dimeric affibody
por: Morito, Takahiro, et al.
Publicado: (2021)

Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain
por: Syvänen, Stina, et al.
Publicado: (2020)

Synthesis and preclinical evaluation of a novel fluorine-18 labeled small-molecule PET radiotracer for Imaging of CXCR3 receptor In mouse models of atherosclerosis
por: Alluri, Santosh R., et al.
Publicado: (2023)

Synthesis and preclinical evaluation of a novel fluorine-18 labeled small-molecule PET radiotracer for imaging of CXCR3 receptor in mouse models of atherosclerosis
por: Alluri, Santosh R., et al.
Publicado: (2023)

The curcumin analogue PAC has potent anti-anaplastic thyroid cancer effects
por: Al-Mohanna, Mai, et al.
Publicado: (2023)

A step-wise synthetic approach is necessary to access γ-conjugates of folate: folate-conjugated prodigiosenes
por: Figliola, Carlotta, et al.
Publicado: (2019)

Enhancement of Binding Affinity of Folate to Its Receptor by Peptide Conjugation
por: Dharmatti, Roopa, et al.
Publicado: (2019)

Mechanistic study of nucleophilic fluorination for the synthesis of fluorine-18 labeled fluoroform with high molar activity from N-difluoromethyltriazolium triflate
por: Chai, Jin Young, et al.
Publicado: (2021)

Synthesis of Regiospecifically Fluorinated Conjugated Dienamides
por: Chowdhury, Mohammad, et al.
Publicado: (2014)

Site-Specific Labeling of scVEGF with Fluorine-18 for Positron Emission Tomography Imaging
por: Wang, Hui, et al.
Publicado: (2012)

A fluorine-18 labeled radiotracer for PET imaging of γ-glutamyltranspeptidase in living subjects
por: Gao, Dingyao, et al.
Publicado: (2021)

Toward Novel [(18)F]Fluorine-Labeled Radiotracers for the Imaging of α-Synuclein Fibrils
por: Uzuegbunam, Bright C., et al.
Publicado: (2022)

Synthesis and preliminary preclinical evaluation of fluorine-18 labelled isatin-4-(4-methoxyphenyl)-3-thiosemicarbazone ([(18)F]4FIMPTC) as a novel PET tracer of P-glycoprotein expression
por: Verbeek, Joost, et al.
Publicado: (2018)

Mucinous urachal adenocarcinoma: A potential nonfluorodeoxyglucose-avid pitfall on (18)fluorine-fluorodeoxyglucose positron emission tomography/computed tomography
por: Das, Jeeban Paul, et al.
Publicado: (2020)

Ruthenium-Mediated (18)F-Fluorination and Preclinical Evaluation of a New CB(1) Receptor Imaging Agent [(18)F]FPATPP
por: Lahdenpohja, Salla, et al.
Publicado: (2020)

Prevalence, incidence and molecular characterization of tape worms in Al Taif governorate, KSA and the effectiveness of Spirulina platensis as a biological control in vitro
por: Al-Otaibi, Bedor O., et al.
Publicado: (2021)

PAC down-regulates estrogen receptor alpha and suppresses epithelial-to-mesenchymal transition in breast cancer cells
por: Al-Howail, Huda A., et al.
Publicado: (2016)

Functional coating of liposomes using a folate– polymer conjugate to target folate receptors
por: Watanabe, Kazuo, et al.
Publicado: (2012)

Fully automated (18)F-fluorination of N-succinimidyl-4-[(18)F]fluorobenzoate ([(18)F]SFB) for indirect labelling of nanobodies
por: Nagachinta, Surasa, et al.
Publicado: (2022)

Preparation and biodistribution of (188)Re-labeled folate conjugated human serum albumin magnetic cisplatin nanoparticles ((188)Re-folate-CDDP/HSA MNPs) in vivo
por: Tang, Qiu-Sha, et al.
Publicado: (2011)

Sulfonium Salts as Leaving Groups for Aromatic Labelling of Drug-like Small Molecules with Fluorine-18
por: Sander, Kerstin, et al.
Publicado: (2015)

Reduction of the fluorine-18-labeled fluorodeoxyglucose dose for clinically dedicated breast positron emission tomography
por: Satoh, Yoko, et al.
Publicado: (2019)

Pyrazoles as Key Scaffolds for the Development of Fluorine-18-Labeled Radiotracers for Positron Emission Tomography (PET)
por: Gomes, Pedro M. O., et al.
Publicado: (2020)

Rhenium(i) complexation–dissociation strategy for synthesising fluorine-18 labelled pyridine bidentate radiotracers
por: Klenner, Mitchell A., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_c1ce967kcc91ciod9cneoikarg