Site-specific antigen-adjuvant conjugation using cell-free protein synthesis enhances antigen presentation and CD8(+) T-cell response

Antigen-adjuvant conjugation is known to enhance antigen-specific T-cell production in vaccine models, but scalable methods are required to generate site-specific conjugation for clinical translation of this technique. We report the use of the cell-free protein synthesis (CFPS) platform as a rapid m...

Descripción completa

Detalles Bibliográficos
Autores principales: Weiss, Adam M., Ajit, Jainu, Albin, Tyler J., Kapoor, Neeraj, Maroju, Shilpa, Berges, Aym, Pill, Lucy, Fairman, Jeff, Esser-Kahn, Aaron P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973483/
https://www.ncbi.nlm.nih.gov/pubmed/33737644
http://dx.doi.org/10.1038/s41598-021-85709-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973483/
https://www.ncbi.nlm.nih.gov/pubmed/33737644
http://dx.doi.org/10.1038/s41598-021-85709-1

Ejemplares similares