Cargando…

Ethyl pyruvate ameliorate inflammatory response of sinonasal mucosa by inhibiting HMGB1 in rats with acute rhinosinusitis

High mobility group box 1 (HMGB1) has been known to involve in the pathogenesis of many inflammatory diseases. The aim of this study was to establish animal model of acute rhinosinusitis (ARS), and determine whether ethyl pyruvate (EP) attenuate inflammatory response of sinonasal mucosa by inhibitin...

Descripción completa

Detalles Bibliográficos
Autores principales: Liang, Xiang, Shen, Yang, Zhang, Xiaowei, He, Guangxiang, Tan, Guolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973487/
https://www.ncbi.nlm.nih.gov/pubmed/33737667
http://dx.doi.org/10.1038/s41598-021-85785-3