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Swiss-PO: a new tool to analyze the impact of mutations on protein three-dimensional structures for precision oncology

Swiss-PO is a new web tool to map gene mutations on the 3D structure of corresponding proteins and to intuitively assess the structural implications of protein variants for precision oncology. Swiss-PO is constructed around a manually curated database of 3D structures, variant annotations, and seque...

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Detalles Bibliográficos
Autores principales: Krebs, Fanny S., Zoete, Vincent, Trottet, Maxence, Pouchon, Timothée, Bovigny, Christophe, Michielin, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973488/
https://www.ncbi.nlm.nih.gov/pubmed/33737716
http://dx.doi.org/10.1038/s41698-021-00156-5