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Swiss-PO: a new tool to analyze the impact of mutations on protein three-dimensional structures for precision oncology
Swiss-PO is a new web tool to map gene mutations on the 3D structure of corresponding proteins and to intuitively assess the structural implications of protein variants for precision oncology. Swiss-PO is constructed around a manually curated database of 3D structures, variant annotations, and seque...
Autores principales: | Krebs, Fanny S., Zoete, Vincent, Trottet, Maxence, Pouchon, Timothée, Bovigny, Christophe, Michielin, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973488/ https://www.ncbi.nlm.nih.gov/pubmed/33737716 http://dx.doi.org/10.1038/s41698-021-00156-5 |
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