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Experimental modulation of Interleukin 1 shows its key role in chronic kidney disease progression and anemia
Inflammation in chronic kidney disease (CKD) is mostly due to activation of the innate immune system, in which Interleukin-1 (IL-1) is a key player. Anemia of CKD may also be due to erythropoietin (EPO) resistance, clinically associated with inflammation. IL-1 receptor antagonist knockout (RaKO) mic...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973507/ https://www.ncbi.nlm.nih.gov/pubmed/33737665 http://dx.doi.org/10.1038/s41598-021-85778-2 |