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Impact of pre- and post-variant filtration strategies on imputation

Quality control (QC) methods for genome-wide association studies and fine mapping are commonly used for imputation, however they result in loss of many single nucleotide polymorphisms (SNPs). To investigate the consequences of filtration on imputation, we studied the direct effects on the number of...

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Detalles Bibliográficos
Autores principales: Charon, Céline, Allodji, Rodrigue, Meyer, Vincent, Deleuze, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973508/
https://www.ncbi.nlm.nih.gov/pubmed/33737531
http://dx.doi.org/10.1038/s41598-021-85333-z