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Differential role of SIRT1/MAPK pathway during cerebral ischemia in rats and humans
Cerebral ischemia (CI) is a severe cause of neurological dysfunction and mortality. Sirtuin-1 (Silent information regulator family protein 1, SIRT1), an oxidized nicotinamide adenine dinucleotide (NAD(+))-dependent protein deacetylase, plays an important role in protection against several neurodegen...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973546/ https://www.ncbi.nlm.nih.gov/pubmed/33737560 http://dx.doi.org/10.1038/s41598-021-85577-9 |