A dose-escalating toxicology study of the candidate biologic ELP-VEGF

Vascular Endothelial Growth Factor (VEGF), a key mediator of angiogenesis and vascular repair, is reduced in chronic ischemic renal diseases, leading to microvascular rarefaction and deterioration of renal function. We developed a chimeric fusion of human VEGF-A(121) with the carrier protein Elastin...

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Detalles Bibliográficos
Autores principales: Waller, Jamarius P., Burke, Stephen P., Engel, Jason, Chade, Alejandro R., Bidwell, Gene L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973730/
https://www.ncbi.nlm.nih.gov/pubmed/33737643
http://dx.doi.org/10.1038/s41598-021-85693-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973730/
https://www.ncbi.nlm.nih.gov/pubmed/33737643
http://dx.doi.org/10.1038/s41598-021-85693-6

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