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A dose-escalating toxicology study of the candidate biologic ELP-VEGF
Vascular Endothelial Growth Factor (VEGF), a key mediator of angiogenesis and vascular repair, is reduced in chronic ischemic renal diseases, leading to microvascular rarefaction and deterioration of renal function. We developed a chimeric fusion of human VEGF-A(121) with the carrier protein Elastin...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973730/ https://www.ncbi.nlm.nih.gov/pubmed/33737643 http://dx.doi.org/10.1038/s41598-021-85693-6 |