Cargando…

Suppressor of cytokine signaling-1 mimetic peptides attenuate lymphocyte activation in the MRL/lpr mouse autoimmune model

Autoimmune diseases are driven largely by a pathogenic cytokine milieu produced by aberrantly activated lymphocytes. Many cytokines, including interferon gamma (IFN-γ), utilize the JAK/STAT pathway for signal propagation. Suppressor of Cytokine Signaling-1 (SOCS1) is an inducible, intracellular prot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sharma, Jatin, Collins, Teresa D., Roach, Tracoyia, Mishra, Shiwangi, Lam, Brandon K., Mohamed, Zaynab Sidi, Veal, Antia E., Polk, Timothy B., Jones, Amari, Cornaby, Caleb, Haider, Mohammed I., Zeumer-Spataro, Leilani, Johnson, Howard M., Morel, Laurence M., Larkin, Joseph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973732/ https://www.ncbi.nlm.nih.gov/pubmed/33737712 http://dx.doi.org/10.1038/s41598-021-86017-4

Ejemplares similares

Self-Reactivity and the Expression of Memory Markers Vary Independently in MRL-Mp+/+ and MRL-Mp-lpr/lpr Mice
por: Smyth, Lesley, et al.
Publicado: (1992)

Nitric oxide as an inflammatory mediator in autoimmune MRL-lpr/lpr mice.
por: Weinberg, J B
Publicado: (1998)

Immunomodulatory effects of atorvastatin on MRL/lpr mice
por: Sun, Jing, et al.
Publicado: (2022)

Defective maintenance of T cell tolerance to a superantigen in MRL- lpr/lpr mice
Publicado: (1992)

Anti-RNA polymerase I antibodies in sera of MRL lpr/lpr and MRL +/+ autoimmune mice. Correlation of antibody production with delayed onset of lupus-like disease in MRL +/+ mice
Publicado: (1985)

The contribution of L3T4+ T cells to lymphoproliferation and autoantibody production in MRL-lpr/lpr mice
Publicado: (1988)

Reduced receptor editing in lupus-prone MRL/lpr mice
por: Lamoureux, Jennifer L., et al.
Publicado: (2007)

Complement Properdin Determines Disease Activity in MRL/lpr Mice
por: Alaridhee, Hasanain, et al.
Publicado: (2020)

ALW peptide ameliorates lupus nephritis in MRL/lpr mice
por: Wang, Huixia, et al.
Publicado: (2019)

Monoclonal IgM rheumatoid factors derived from arthritic MRL/Mp-lpr/lpr mice
Publicado: (1983)

Beneficial Effect of Bupleurum Polysaccharides on Autoimmune-Prone MRL-lpr Mice
por: Jiang, Yi-Wen, et al.
Publicado: (2012)

Murine lupus is neutrophil elastase-independent in the MRL.Fas(lpr) model
por: Gordon, Rachael A., et al.
Publicado: (2020)

Clinical and Serologic Manifestations of Autoimmune Disease in MRL-lpr/lpr Mice Lacking Nitric Oxide Synthase Type 2
por: Gilkeson, Gary S., et al.
Publicado: (1997)

Influence of thymic genotype on the systemic lupus erythematosus-like disease and T cell proliferation of MRL/Mp-lpr/lpr mice
Publicado: (1981)

Formation of different abzymes in autoimmune-prone MRL-lpr/lpr mice is associated with changes in colony formation of haematopoietic progenitors
por: Andryushkova, Alexandra A, et al.
Publicado: (2007)

Analysis of C4 and the C4 binding protein in the MRL/lpr mouse
por: Wenderfer, Scott E, et al.
Publicado: (2007)

Reduction of lupus nephritis in MRL/lpr mice by a bacterial superantigen treatment
Publicado: (1991)

The MRL/lpr Mouse Strain as a Model for Neuropsychiatric Systemic Lupus Erythematosus
por: Gulinello, Maria, et al.
Publicado: (2011)

Enhanced activation of dendritic cells by autologous apoptotic microvesicles in MRL/lpr mice
por: Dieker, Jürgen, et al.
Publicado: (2015)

Glucocorticoid prevents CD138 expression in T cells of autoimmune MRL/lpr mice
por: Xie, Tianhong, et al.
Publicado: (2022)

Fecal microbiota from MRL/lpr mice exacerbates pristane-induced lupus
por: Yi, Xiaoqing, et al.
Publicado: (2023)

Parallel sets of autoantibodies in MRL-lpr/lpr mice. An anti-DNA, anti- SmRNP, anti-gp70 network
Publicado: (1987)

Genetic Variations Controlling Regulatory T Cell Development and Activity in Mouse Models of Lupus-Like Autoimmunity
por: Roach, Tracoyia, et al.
Publicado: (2022)

Prolactin Levels Correlate with Abnormal B Cell Maturation in MRL and MRL/lpr Mouse Models of Systemic Lupus Erythematosus-Like Disease
por: Legorreta-Haquet, Maria Victoria, et al.
Publicado: (2013)

Prevention of nephritis in major histocompatibility complex class II- deficient MRL-lpr mice
Publicado: (1994)

Spontaneous production of tumor necrosis factor alpha by Kupffer cells of MRL/lpr mice
Publicado: (1988)

Defects in the Peripheral Taste Structure and Function in the MRL/lpr Mouse Model of Autoimmune Disease
por: Kim, Agnes, et al.
Publicado: (2012)

Diagnosis and early detection of CNS-SLE in MRL/lpr mice using peptide microarrays
por: Williams, Stephanie, et al.
Publicado: (2014)

Prevention of Immune Nephritis by the Small Molecular Weight Immunomodulator Iguratimod in MRL/lpr Mice
por: Yan, Qingran, et al.
Publicado: (2014)

Deletion of IL-18 Expression Ameliorates Spontaneous Kidney Failure in MRL(lpr) Mice
por: Schirmer, Bastian, et al.
Publicado: (2015)

Alterations of the Gut Microbiota Associated With Promoting Efficacy of Prednisone by Bromofuranone in MRL/lpr Mice
por: He, Zhixing, et al.
Publicado: (2019)

Dexamethasone reduces autoantibody levels in MRL/lpr mice by inhibiting Tfh cell responses
por: Shen, Chunxiu, et al.
Publicado: (2021)

CD138 promotes the accumulation and activation of autoreactive T cells in autoimmune MRL/lpr mice
por: Xie, Tianhong, et al.
Publicado: (2023)

MRL-lpr/lpr Mice Exhibit a Defect in Maintaining Developmental Arrest and Follicular Exclusion of Anti–double-stranded DNA B Cells
por: Mandik-Nayak, Laura, et al.
Publicado: (1999)

Incorporation, distribution, and turnover of arachidonic acid within membrane phospholipids of B220+ T cells from autoimmune-prone MRL- lpr/lpr mice
Publicado: (1990)

Liver is a possible site for the proliferation of abnormal CD3+4-8- double-negative lymphocytes in autoimmune MRL-lpr/lpr mice
Publicado: (1990)

The defect in Fas mRNA expression in MRL/lpr mice is associated with insertion of the retrotransposon, ETn
Publicado: (1993)

Efficient Peripheral Clonal Elimination of B Lymphocytes in MRL/lpr Mice Bearing Autoantibody Transgenes
por: Kench, Jennifer A., et al.
Publicado: (1998)

Anti–DNA B Cells in MRL/lpr Mice Show Altered Differentiation and Editing Pattern
por: Li, Yijin, et al.
Publicado: (2002)

IgG3 deficiency extends lifespan and attenuates progression of glomerulonephritis in MRL/lpr mice
por: Greenspan, Neil S, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_donj0oqakdsoc68sfhg9qcagu3