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Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo

Age-related macular degeneration (AMD) is the primary cause of blindness in adults over 60 years of age, and clinical trials are currently assessing the therapeutic potential of retinal pigmented epithelial (RPE) cell monolayers on implantable scaffolds to treat this disease. However, challenges rel...

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Detalles Bibliográficos
Autores principales: Pennington, Britney O., Bailey, Jeffrey K., Faynus, Mohamed A., Hinman, Cassidy, Hee, Mitchell N., Ritts, Rory, Nadar, Vignesh, Zhu, Danhong, Mitra, Debbie, Martinez-Camarillo, Juan Carlos, Lin, Tai-Chi, Thomas, Biju B., Hinton, David R., Humayun, Mark S., Lebkowski, Jane, Johnson, Lincoln V., Clegg, Dennis O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973769/
https://www.ncbi.nlm.nih.gov/pubmed/33737600
http://dx.doi.org/10.1038/s41598-021-85631-6