Molecular docking, pharmacokinetic studies, and in vivo pharmacological study of indole derivative 2-(5-methoxy-2-methyl-1H-indole-3-yl)-N′-[(E)-(3-nitrophenyl) methylidene] acetohydrazide as a promising chemoprotective agent against cisplatin induced organ damage

Cisplatin is an efficient anticancer drug against various types of cancers however, its usage involves side effects. We investigated the mechanisms of action of indole derivative, 2-(5-methoxy-2-methyl-1H-indol-3-yl)-N'-[(E)-(3-nitrophenyl) methylidene] acetohydrazide (MMINA) against anticancer...

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Detalles Bibliográficos
Autores principales: Razak, Suhail, Afsar, Tayyaba, Bibi, Nousheen, Abulmeaty, Mahmoud, Qamar, Wajhul, Almajwal, Ali, Inam, Anam, Al Disi, Dara, Shabbir, Maria, Bhat, Mashooq Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973782/
https://www.ncbi.nlm.nih.gov/pubmed/33737575
http://dx.doi.org/10.1038/s41598-021-84748-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973782/
https://www.ncbi.nlm.nih.gov/pubmed/33737575
http://dx.doi.org/10.1038/s41598-021-84748-y

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