Cargando…

Effects of SLC22A2 808G>T polymorphism and bosutinib concentrations on serum creatinine in patients with chronic myeloid leukemia receiving bosutinib therapy

The purpose of this study was to investigate the effects of SLC22A2 808G>T polymorphism and trough concentrations (C(0)) of bosutinib on serum creatinine in 28 patients taking bosutinib. At 1, 3, 6, 12, 24, and 36 months after administration, analysis of bosutinib C(0) and creatinine was performe...

Descripción completa

Detalles Bibliográficos
Autores principales: Abumiya, Maiko, Takahashi, Naoto, Takahashi, Saori, Yoshioka, Tomoko, Kameoka, Yoshihiro, Miura, Masatomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973796/
https://www.ncbi.nlm.nih.gov/pubmed/33737618
http://dx.doi.org/10.1038/s41598-021-85757-7