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The flavonoid 7,8-DHF fosters prenatal brain proliferation potency in a mouse model of Down syndrome

Neurogenesis impairment is a key determinant of intellectual disability in Down syndrome (DS), a genetic pathology due to triplication of chromosome 21. Since neurogenesis ceases after birth, apart in the hippocampus and olfactory bulb, the only means to tackle the problem of neurogenesis impairment...

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Detalles Bibliográficos
Autores principales: Stagni, Fiorenza, Uguagliati, Beatrice, Emili, Marco, Giacomini, Andrea, Bartesaghi, Renata, Guidi, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973813/
https://www.ncbi.nlm.nih.gov/pubmed/33737521
http://dx.doi.org/10.1038/s41598-021-85284-5