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The flavonoid 7,8-DHF fosters prenatal brain proliferation potency in a mouse model of Down syndrome
Neurogenesis impairment is a key determinant of intellectual disability in Down syndrome (DS), a genetic pathology due to triplication of chromosome 21. Since neurogenesis ceases after birth, apart in the hippocampus and olfactory bulb, the only means to tackle the problem of neurogenesis impairment...
Autores principales: | Stagni, Fiorenza, Uguagliati, Beatrice, Emili, Marco, Giacomini, Andrea, Bartesaghi, Renata, Guidi, Sandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973813/ https://www.ncbi.nlm.nih.gov/pubmed/33737521 http://dx.doi.org/10.1038/s41598-021-85284-5 |
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