A virtuous cycle operated by ERp44 and ERGIC-53 guarantees proteostasis in the early secretory compartment

The composition of the secretome depends on the combined action of cargo receptors that facilitate protein transport and sequential checkpoints that restrict it to native conformers. Acting after endoplasmic reticulum (ER)-resident chaperones, ERp44 retrieves its clients from downstream compartments...

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Detalles Bibliográficos
Autores principales: Tempio, Tiziana, Orsi, Andrea, Sicari, Daria, Valetti, Caterina, Yoboue, Edgar Djaha, Anelli, Tiziana, Sitia, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973864/
https://www.ncbi.nlm.nih.gov/pubmed/33763635
http://dx.doi.org/10.1016/j.isci.2021.102244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973864/
https://www.ncbi.nlm.nih.gov/pubmed/33763635
http://dx.doi.org/10.1016/j.isci.2021.102244

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