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A virtuous cycle operated by ERp44 and ERGIC-53 guarantees proteostasis in the early secretory compartment
The composition of the secretome depends on the combined action of cargo receptors that facilitate protein transport and sequential checkpoints that restrict it to native conformers. Acting after endoplasmic reticulum (ER)-resident chaperones, ERp44 retrieves its clients from downstream compartments...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973864/ https://www.ncbi.nlm.nih.gov/pubmed/33763635 http://dx.doi.org/10.1016/j.isci.2021.102244 |