MicroRNA-181a suppresses norethisterone-promoted tumorigenesis of breast epithelial MCF10A cells through the PGRMC1/EGFR–PI3K/Akt/mTOR signaling pathway

BACKGROUND: Research suggests that hormone replacement therapy may increase the risk of breast cancer, and progestins such as norethisterone (NET) play a key role in this phenomenon. We have demonstrated that microRNA-181a (miR-181a) suppresses NET-promoted breast cancer cell survival. Nonetheless,...

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Detalles Bibliográficos
Autores principales: Cai, Guiju, Wang, Yuejiao, Houda, Tahiri, Yang, Chun, Wang, Lijuan, Gu, Muqing, Mueck, Alfred, Croteau, Stephane, Ruan, Xiangyan, Hardy, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974027/
https://www.ncbi.nlm.nih.gov/pubmed/33730679
http://dx.doi.org/10.1016/j.tranon.2021.101068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974027/
https://www.ncbi.nlm.nih.gov/pubmed/33730679
http://dx.doi.org/10.1016/j.tranon.2021.101068

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