Backbone NMR assignments of the C-terminal domain of the human prion protein and its disease‐associated T183A variant

Transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative disorders associated with the misfolding and aggregation of the human prion protein (huPrP). Despite efforts into investigating the process of huPrP aggregation, the mechanisms triggering its misfolding remain elusive. A nu...

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Detalles Bibliográficos
Autores principales: Sanz-Hernández, Máximo, De Simone, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974147/
https://www.ncbi.nlm.nih.gov/pubmed/33590433
http://dx.doi.org/10.1007/s12104-021-10005-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974147/
https://www.ncbi.nlm.nih.gov/pubmed/33590433
http://dx.doi.org/10.1007/s12104-021-10005-y

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